"Greater consumption was associated with an increase in longitudinal MSSS (p < 0.001); similar findings were noted when the EDSS was used as the disability outcome. Smoking during the cohort period was not associated with relapse (cumulative pack years smoked after cohort entry: hazard ratio 0.94 per pack year, 95% CI 0.69–1.26).
A meta-analysis of four studies concluded that there was significant between-study heterogeneity and a trend towards smoking increasing the risk of secondary progressive MS (relative risk 1.88, 95% CI 0.98–3.61, p = 0.06) [Handel et al. 2011].
Little is known about the effects of smoking on response to disease-modifying MS therapies. A small study of 31 MS patients using subcutaneous interferon-β revealed that smokers had a much greater risk of developing neutralizing antibodies that abrogate the effectiveness of the drug [Sena et al. 2010]."
Badania z 2012, Wingerchuk.
Więc - nie powoduje rzutów/ nie zwiększa ryzyka rzutów, ale przyśpiesza przejście we wtórnie postępującą postać.
Co nie znaczy, że ktoś od razu musi rzucić w dniu diagnozy, ale - stopniowo, w ciągu paru miesięcy - na prawdę warto.
A meta-analysis of four studies concluded that there was significant between-study heterogeneity and a trend towards smoking increasing the risk of secondary progressive MS (relative risk 1.88, 95% CI 0.98–3.61, p = 0.06) [Handel et al. 2011].
Little is known about the effects of smoking on response to disease-modifying MS therapies. A small study of 31 MS patients using subcutaneous interferon-β revealed that smokers had a much greater risk of developing neutralizing antibodies that abrogate the effectiveness of the drug [Sena et al. 2010]."
Badania z 2012, Wingerchuk.
Więc - nie powoduje rzutów/ nie zwiększa ryzyka rzutów, ale przyśpiesza przejście we wtórnie postępującą postać.
Co nie znaczy, że ktoś od razu musi rzucić w dniu diagnozy, ale - stopniowo, w ciągu paru miesięcy - na prawdę warto.